Published research
Find our latest research on cocoa flavanols, in collaboration with a global network of scientific partners
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Brain/Cognitive Health
Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice.
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Cardiovascular
Sustained increase in flow-mediated dilation after daily intake of high-flavanol cocoa drink over 1 week.
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Microbiome
Immune effects of cocoa procyanidin oligomers on peripheral blood mononuclear cells.
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Biological Effects
Consumption of flavanol-rich cocoa acutely increases microcirculation in human skin.
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Biological Effects
Cocoa flavanol-enriched snack bars containing phytosterols effectively lower total and low-density lipoprotein cholester
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Cardiovascular
Procyanidins protect Caco-2 cells from bile acid- and oxidant-induced damage.
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Cardiovascular
Inhibitory effects of procyanidin B(2) dimer on lipid-laden macrophage formation.
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Biological Effects
The effect of cocoa polyphenols on the growth, metabolism, and biofilm formation by Streptococcus mutans and Streptococcus sanguinis.
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Cardiovascular
Flavanols and cardiovascular health: effects on the circulating NO pool in humans.
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Analytical Methods
Predictive Analysis of Cocoa Procyanidins Using Near-Infrared Spectroscopy Techniques
Cardiovascular
Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] suppresses the expression of cyclooxygenase-2 in endotoxin-treated monocytic cells.
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Biological Effects
Long-term ingestion of high flavanol cocoa provides photoprotection against UV-induced erythema and improves skin condition in women.
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Cardiovascular
(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans.
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