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An introduction to cocoa flavanols Cocoa flavanols and chocolate
Cardiovascular & heart health effects of cocoa flavanols The COSMOS trial Cognitive & brain health effects of cocoa flavanols The COSMOS-Web trial Uncover the benefits of flavanols Analytical methods of cocoa flavanol research Research publications
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Research publications

Find our latest research on cocoa flavanols, in collaboration with a global network of scientific partners

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Cardiovascular

Flavanol-rich cocoa drink lowers plasma F(2)-isoprostane concentrations in humans
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Cardiovascular

Pentameric procyanidins isolated from Theobroma cacao seeds selectively downregulate ErbB2 in human aortic endothelial cells
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Analytical Methods

Concentrations of proanthocyanidins in common foods and estimations of normal consumption
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Cardiovascular

Membrane effects of cocoa procyanidins in liposomes and Jurkat T cells
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Cardiovascular

Epicatechin, catechin, and dimeric procyanidins inhibit PMA-induced NF-kappaB activation at multiple steps in Jurkat T cells
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Cardiovascular

Flavanol-rich cocoa induces nitric-oxide-dependent vasodilation in healthy humans
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Chemistry

Inhibition of angiotensin converting enzyme (ACE) activity by flavan-3-ols and procyanidins
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Cardiovascular

Nutrition: Milk and absorption of dietary flavanols
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Analytical Methods

Screening of foods containing proanthocyanidins and their structural characterization using LC-MS/MS and thiolytic degradation
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Analytical Methods

Liquid chromatographic/electrospray ionization mass spectrometric studies of proanthocyanidins in foods
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Cardiovascular

Vascular Effects of Cocoa Rich in Flavan-3-ols
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Absorption & Metabolism

Food effects on the absorption and pharmacokinetics of cocoa flavanols
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Cardiovascular

Dietary flavanols and procyanidin oligomers from cocoa (Theobroma cacao) inhibit platelet function
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Chemistry

Chocolate intake increases urinary excretion of polyphenol-derived phenolic acids in healthy human subjects
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Biological Effects

Studies in polyphenol chemistry and bioactivity. 4.(1) Synthesis of trimeric, tetrameric, pentameric, and higher oligomeric epicatechin-derived procyanidins having all-4beta,8-interflavan connectivity and their inhibition of cancer cell growth through cel
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